Investigating matrix interference in the pharmacopeial limit test for aluminum in citric acid: a re-examination, for revision of the method
In many pharmacopoeias, the limit test used for determining the level of aluminum in citric acid labeled for use in the manufacture of dialysate, is based on solvent extraction using 8-hydroxyquinoline and measurement of fluorescence.However, the fluorescence intensity (F.I.) readout from the extract of citric acid samples has been found to diamond